Spirostanol Sapogenins from the Underground Parts of Tupistra chinensis

Abstract

Chemical examination of the underground parts of Tupistra chinensis led to the isolation of two new 5β-spirostane type steroidal sapogenins, tupichigenin B (1) and C (2), together with two known steroidal sapogenins, ranmogenin A (3) and Δ²⁵⁽²⁷⁾-pentrogenin (4). The structures of 1 and 2 were established as spirost-25(27)-ene-1β, 3β, 4β, 5β, 6β-pentaol and 1β, 2β, 3β, 4β, 5β-pentahydroxyspirost-25(27)-en-6-one, respectively, on the basis of detailed analysis of their physical and spectral data.