Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Studies on Naphthyridines. III. Syntheses of 2, 10-Diazaanthracene and 1, 7-Naphthyridine.
Nobuo Ikekawa
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1958 Volume 6 Issue 4 Pages 401-404

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Abstract
The reaction of sodium salt of 3-carboxyquinaldine and formaldehyde gave 2-hydroxyethyl-3-quinolinecarboxylic, acid lactone, which was led to the amide, and its oxidation gave 1-hydroxy-2, 10-diazaanthracene. 2, 10-Diazaanthracene was obtained from this 1-hydroxy compound. 1, 7-Naphthyridine was synthesized from 4-chloro-1, 7-naphthyridine via 4-hydrazino compound.
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© The Pharmaceutical Society of Japan
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