Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Catalytic Reduction of 4-Benzyloxy-6-methylpyrimidine and Related Compounds.
山中 宏
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1959 年 7 巻 2 号 p. 158-161

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Catalytic reduction of 4-benzyloxy-6-methylpyrimidine 1-oxide in methanol over palladium-carbon resulted in the formation of 6-methyl-4-pyrimidinol via 4-hydroxy-6-methylpyrimidine 1-oxide. The use of Raney nickel as a catalyst in this case afforded 4-benzyloxy-6-methylpyrimidine and this is a new type of reaction not recorded in past literature.
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© The Pharmaceutical Society of Japan
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