Abstract
Catechol cyclic phosphate (CCP) (IV) was found to be alcoholyzed with several primary and secondary monofunctional alcohols to give the corresponding alkyl or aralkyl ohydroxyphenyl phosphate (V) in a yield of 47∼65%. These reactions proceeded by the catalytic function of the acid reagent, CCP, used. The products (V) were further hydrolyzed by acid or alkali to give the corresponding alcohols and o-hydroxyphenyl phosphate. The catechol moiety of (V) was found inert against catalytic hydrogenolysis, while it was hydrolyzed by snake venom phosphodiesterase to alkyl or aralkyl phosphates.
