Studies on the Nitration of 4-Isoquinolinol and its Derivatives.

Abstract

4-Isoquinolinol was nitrated with potassium nitrate in conc. sulfuric acid to 3-nitro-4-isoquinolinol. Structure of the latter compound was established by conversion to 3-aminoisoquinoline via several steps. Structure of the triacetate of intermediate 3-amino-4-isoquinolinol was also discussed.