Studies on the Constituents of Digitalis purpurea L. XIV. 16-Acetyl and 16-Propionyl Derivatives of Digitalinum Verum.

Abstract

Deacetylation with snail enzyme was carried out on 16-acetyl-and 16-propionyldigitalinum verum monoacetates and the corresponding 16-acetyl-and 16-propionyldigitalinum verum were obtained. Characteristics of these compounds were examined and it was found that the toxicity of 16-acetyldigitalinum verum was far higher than that of the original monoacetate.