Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Studies on the Constituents of Digitalis purpurea L. XIV. 16-Acetyl and 16-Propionyl Derivatives of Digitalinum Verum.
Kazuo MiyatakeAtsuji OkanoKazuhiko HojiTosaku MikiAkio Sakashita
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1959 Volume 7 Issue 5 Pages 634-640

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Abstract

Deacetylation with snail enzyme was carried out on 16-acetyl-and 16-propionyldigitalinum verum monoacetates and the corresponding 16-acetyl-and 16-propionyldigitalinum verum were obtained. Characteristics of these compounds were examined and it was found that the toxicity of 16-acetyldigitalinum verum was far higher than that of the original monoacetate.

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© The Pharmaceutical Society of Japan
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