Author's Organization：Pharmaceutical Institute, Medical School, University of Hokkaido Pharmaceutical Institute, Medical School, University of Hokkaido Pharmaceutical Institute, Medical School, University of Hokkaido Pharmaceutical Institute, Medical School, University of Hokkaido
Isolation of active principles in the ligusticum root (Hokkai-Toki) was attempted. Anticholinergic principles were traced by the Magnus method with rat intestine. Ligustilide, which is a new and the most active constituent was isolated. It is an isomer of butylphthalide. It was marked bluish fluorescence and decomposes rapidly on exposure to air.
