Abstract
For phamacological evaluation, 2, 3-and 3, 4-ethylenedioxy-N-methylmorphinans were prepared. 3, 4-Ethylenedioxyphenylacetic acid was prepared through two different ways; 6-formylbenzodioxane was converted to the amide, from which two N-methylmorphinan were obtained according to the method of Schnider. The Structrues of the two isomeric N-methylmorphinans were cofirmed by infrared spectral data. 3, 4-Ethylenedioxy-N-methylmorphinan was resolved into the optical antipodes, using bibenzoyl-d-tartaric acid.
