Studies on Coenzyme Analogs. VI. The Synthesis of P¹-5'-Adenosine P²-(2-Mercaptoethyl) Pyrophosphate and its Activity as a Coenzyme-A Analog

Abstract

P¹-5'-Adenosine P²-(2-mercaptoethyl) pyrophosphate was prepared by the reaction of adenosine 5'-phosphoramidate dicyclohexylguanidinium salt and 2-mercaptoethyl phosphate. This compound has no activity for acetylation reaction in the pigeon liver enzyme systems.