Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Studies on the Sulfur-containing Chelating Agents. VI. Syntheses of β-Mercapto-acid Esters and their Copper and Nickel Chelates.
Hisashi TanakaAkira Yokoyama
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1961 Volume 9 Issue 2 Pages 110-114

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Abstract
β-Mercapto-p-chlorohydrocinnamic acid, β-mercapto-p-methoxyhydrocinnamic acid, β-mercapto-β-(1-naphthyl) propionic acid, and β-mercapto-β-(2-furyl) propionic acid and their alkyl esters were prepared. These β-mercapto-acid esters formed stable chelates with copper and nickel. The ratio of ligand to the metal was 1 : 1 in copper chelates and 2 : 1 in nickel chelates. The reaction with nickel was particularly sensitive.
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© The Pharmaceutical Society of Japan
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