Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Structure of the Condensation Product of Arylamine and Glucofuranuronolactone.
Shoji Takitani
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1961 Volume 9 Issue 3 Pages 222-226

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Abstract
The condensation products of arylamine (aniline, p-nitroaniline, p-aminoazobenzene, and sulfanilamide) with glucofuranurono-γ-lactone were prepared. It was established that the condensation product should have a structure of 1-arylamino-1-deoxyglucofuranurono-γ-lactone (II a). It was found that the opening of the lactone ring in (II a) by treatment with sodium hydroxide afforded 1-arylamino-1-deoxyglucofuranuronate, while it gave 1-arylamino-1-deoxyglucopyranuronamide with ammonia-saturated methanol.
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© The Pharmaceutical Society of Japan
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