Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Syntheses of Heterocyclic Compounds of Nitrogen. CXXVI. Syntheses of Oxazolopyridines and Related Compounds. (7).
Torizo TakahashiAkira Koshiro
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1961 Volume 9 Issue 6 Pages 426-432

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Abstract
1) 7-Substituted 2-methyl- or 2-phenyl-oxazolo [4, 5-c] pyridines were prepared from 3, 5-dinitro-4-hydroxypyridine and some of them were hydrogenated over palladium-carbon or Raney nickel. 2) By examination of the hydrolysis products of 2-methyl-7-nitro (or bromo)-oxazolo-[4, 5-c] pyridine monomethiodide and 2-methyloxazolo [4, 5-b] pyridine monomethiodide, it was confirmed that methyl iodide combined with nitrogen atom in the pyridine ring of oxazolopyridine system.
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© The Pharmaceutical Society of Japan
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