Studies on Carcinostatic Substances. XXXV. Chemical and Antitumor Properties of Quaternary Derivatives of N-Alkoxy-2, 2'-dichlorodiethylamine.

Abstract

Alkoxy-bis (2-chloroethyl) methylammonium halides were prepared and their chemical reactivity and latent antitumor activity against the Yoshida sarcoma were examined. Chemical mechanism of activation of these compounds was also discussed.