抄録
Freeze-concentration- crystallization of L-phenylalanine was carried out by applying progressive freeze -concentration crystallization. Concentration effectiveness was affected by the advance rate of ice front and the stirring rate at the ice-liquid interface as expected by the concentration polarization model. When the concentration of L-phenylalanine reached the saturation concentration, it began to crystallize proving the feasibility of the simultaneous process of freeze concentration and crystallization. Crystals of L-phenylalanine thus obtained were needle-shaped and easily separable from the concentrated mother solution. The present method seems to be the best method for purification of such thermally unstable materials as medicines and food components.
