Cell Structure and Function
Online ISSN : 1347-3700
Print ISSN : 0386-7196
ISSN-L : 0386-7196
The Inhibition of Platelet Aggregation by Biscoclaurine Alkaloids
Sadahiro Watanabe, Yasuko M.Morimoto, Noriyuki Shiraishi, Akiyoshi Sano, Kozo Utsumi
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1981 Volume 6 Issue 3 Pages 263-267

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Abstract

The effects of biscoclaurine alkaloids on ADP-or collagen-induced platelet aggregation were examined as alkaloids are known to inhibit lipid peroxidation (1, 7) and stabilize labilized biomembranes (8, 9). Most alkaloids greatly inhibit the platelet aggregation induced by ADP or collagen. This inhibition was concentration dependent and significantly higher where there was collagen aggregation.

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© Japan Society for Cell Biology
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