Drug Delivery System
Online ISSN : 1881-2732
Print ISSN : 0913-5006
ISSN-L : 0913-5006
感染症とDDS
ウイルス感染症とDDS
東海林 洋子
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ジャーナル フリー

2000 年 15 巻 3 号 p. 171-177

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Virus infections are divided according to organ level such as respiratory apparatus infection, upper respiratory infection, lower respiratory tract infection, hepatitis, urinary tract infection and etc. since virus has organ specificity (tropism) Obvious locus of infection would make it convenient to design targeting pharmaceutical drug. However, antigen of influenza virus and human acquired immune deficiency virus (HIV) are frequently altered as well as others. Because of frequent alteration of target molecule, cellular targeting is never easy. Current available anti viral drugs are made targeted toward metabolic products of virus. Other type of and viral drugs are designed targeted viral gene like antisense drugs. Gene medicine itself would be categorized as target therapeutic agent. I will address the gene medicine which have been enthusiastically developed in addition to the current anti viral drugs.
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