Drug Delivery System
Online ISSN : 1881-2732
Print ISSN : 0913-5006
ISSN-L : 0913-5006
テイラーメイドメディスンとDDS
定量的PCRによる新しい遺伝子発現プロファイルシステムの構築—臨床および創薬への応用—
川口 辰哉John C. Cheronis満屋 裕明
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2002 年 17 巻 2 号 p. 119-126

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Innovation of gene technologies such as DNA microarray and real-time PCR has made it possible to quantitatively measure the expression of multiple genes. Such new technologies are expected to advance clinical medicine and pave new avenues for drug development. Source Precision MedicineTM, a biotechnology company with which we have been working, has recently established a novel gene-expression profiling system using quantitative PCR in order to construct data bases of genetic profiles of individual patients upon therapy and disease progression. We here describe the system and recent data of the gene profiles associated with inflammatory processes, and discuss advantages of the use of the system for diagnosis/therapy and drug development.
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