Drug Discoveries & Therapeutics
Online ISSN : 1881-784X
Print ISSN : 1881-7831
ISSN-L : 1881-7831
Brief Reports
Isotryptoquivaline F, a new quinazolinone derivative with anti TNF-α activity from Aspergillus sp. CM9a
Heng XueQingyan XuChunhua LuYuemao Shen
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JOURNALS FREE ACCESS

2014 Volume 8 Issue 5 Pages 208-211

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Abstract

Isotryptoquivaline F (1) was isolated from Aspergillus sp. CM9a, an endophytic fungus of Cephalotaxus mannii. The structure was elucidated by extensively 1D and 2D NMR and HR ESI MS spectroscopy. It has good TNF-α antagonistic effect, and can be used for anti-inflammatory drugs or other bioactive leading drugs.

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© 2014 International Research and Cooperation Association for Bio & Socio-Sciences Advancement
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