Dental Materials Journal
Online ISSN : 1881-1361
Print ISSN : 0287-4547
ISSN-L : 0287-4547
Original Paper
Surface-tethering of methylated polyrotaxanes with 4-vinylbenzyl groups onto poly(ether ether ketone) substrates for improving osteoblast compatibility
Yoshinori ARISAKAMasahiro HAKARIYATakanori IWATAHiroki MASUDATetsuya YODAAtsushi TAMURANobuhiko YUI
Author information

2021 Volume 40 Issue 3 Pages 813-819


Poly(ether ether ketone) (PEEK) is a high-performance thermoplastic used for several industrial applications due to its excellent mechanical properties. However, the use of PEEK is limited to dental materials because of its poor implant-bone integration. In the present study, methylated polyrotaxanes (MePRXs) with 4-vinylbenzyl groups, which are supermolecules composed of methylated α-cyclodextrins and poly(ethylene glycol) chains end-capped with 4-vinylbenzyl groups, were covalently tethered onto PEEK surfaces using photo-induced polymerization to improve their osteoblast compatibility. The surface-tethering of MePRXs onto PEEK surfaces was confirmed by analyzing their attenuated total reflectance Fourier transform infrared spectra and contact angles. When mouse preosteoblasts were cultured on the MePRX-PEEK and bare PEEK surfaces, the MePRX-PEEK surfaces showed significantly better proliferation and osteoblast differentiation than the bare PEEK surfaces. These results suggest that surface modification of PEEKs using MePRXs improves their osteoblast compatibility.

Content from these authors
© 2021 The Japanese Society for Dental Materials and Devices
Previous article Next article