1990 Volume 9 Issue 1 Pages 100-107,124
The interaction of methyl methacrylate (MMA), ethylene dimethacrylate (EDMA) and triethyleneglycol dimethacrylate (TEGDMA), which are widely used in dentistry, with the dipalmitoyl phosphatidylcholine (DPPC) and the DPPC/cholesterol (CS) liposome system was studied by 1H and 13C nuclear magnetic resonance spectroscopy (NMR). EDMA and TEGDMA have a larger interaction with the DPPC liposome system compared to MMA, resulting in changes in chemical shifts. The 13C chemical shift differences of C=C-C-O were larger than those of other carbon portions in methacrylate, indicating that double bonds interact predominantly with DPPC liposomes due to the hydrophobicity of methacrylates. At 37°C, 1H signals from TEGDMA appeared in the DPPC/CS/TEGDMA liposome system, while signals due to H2C=C-C-OCH2CH2 did not appear in the DPPC/TEGDMA liposome system.