抄録
Stress-induced gonadotropin secretion was investigated in both sexes in relation to limbic participation in its mechanisms. Application of the immobilizationstress induced the release of serum corticosterone in intact females, males and orchidectomized estrogen-primed males. Serum prolactin was also increased by the stress in females and orchidectomized estrogen-primed males, but not in intact males. Hippocampal ablation did not affect the stress-induced release of corticosterone and prolactin.
Serum LH was neither increased nor decreased by the stress in intact females and males, but it was increased in orchidectomized estrogen-primed males. Hippocampal ablation, however, brought about LH release in stressed females and abolished stressinduced increase in LH in orchidectomized estrogen primed males.
Stress increased serum or pituitary FSH in females and orchidectomized estrogenprimed males, but this effect was suppressed by hippocampal ablation.
Thus, there is a sex differentiation in stress-induced gonadotropin and prolactin secretions, and the hippocampus may be involved in its control mechanism.
