抄録
A new humoral factor of the anterior hypothalamus was found to possess a powerful activity in stimulating the liberation of hypophyseal thyrotrophin and enlarging the thyroid gland. This humoral factor seemed to be released from the hypothalamic-neurohypophyseal neurosecretory system in blood and urine. Administration of methylthiouracil provoked not only an enlargement of the thyroid but also a marked elevation of the neurosecretion of the Ncl. supraopticus or paraventricularis. On the contrary, thyroxin and chlorpromazine suppressed the release of pituitary thyrotrophin and hypothalamic neurosecretion.
It seemed likely that the thyrotroph-thyroidal function is under the control of the neurohumor of the anterior hypothalamic neurosecretory system.
