STUDIES ON THE THYROID UPTAKE OF I¹³¹ 3. EFFECT OF VARIOUS HORMONES OTHER THAN THE PITUITARY

Abstract

Using rats of Wistar strain, the effect of various hormones other than the pituitary on the uptake of I¹³¹ by the thyroid (2hours value) was investigated.
Of the tested adrenal hormones including synthetic ones with enhanced activity, cortisone as well as epinephrine and norepinephrine decreased I¹³¹ uptake by the thyroid.
Of the gonadal hormones tested, only estradiol increased it significantly in male rats, but insignificantly in female. Testosterone propionate and androsterone tended to decrease it in male and progesterone acted in a similar manner in both male and female.
Insulin and thyroxin elicited significant decrease in thyroid uptake of I¹³¹.
Neither parathyroid nor salivary gland hormones produced remarkable change in it.