Endocrinologia Japonica
Online ISSN : 2185-6370
Print ISSN : 0013-7219
ISSN-L : 0013-7219
STUDIES ON INTRAVENOUS GLUCOSE TOLERANCE CURVE 2. EXPERIMENTS WITH RABBITS
KATSUMI FUKUSHIMA
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1957 年 4 巻 3 号 p. 155-161

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抄録
1) Eighteen male and 18 female rabbits were intravenously injected with glucose and curves representing change in blood sugar level were classified into 4 types-exponential, humped curve, sigmoid and straight line-the frequency of each type being investigated.It was found out that the humped curve type had the highest frequecy for the rabbit occurring in half of all the examined cases, and the exponential type only in 1/4.There was no difference by sex in the frequency.
2) Animals of the humped curve, the sigmoid and the straight line types tended to have lower insulin sensitivity.
3) The administration of insulin tended to transform all types other than the exponential one into this.This effect was more evidently demonstrated when zinc-protamin-insulin was subcutaneously injected 20hours before the glucose administration than when the regular insulin was given together with glucose.
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© The Japan Endocrine Society
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