STUDIES ON THE SALIVARY GLAND HORMONES LABELED WITH I¹³¹ 5: LOCALIZATION OF RADIOACTIVITY AFTER ADMINISTRATION OF I¹³¹-LABELED SALIVA-PAROTIN-A TO RATS

STUDIES ON THE SALIVARY GLAND HORMONES XXXVI

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A Parotin-like substance, Saliva-Parotin-A, isolated from human saliva, was labeled with radioactive iodine. The biological activity of the radioiodinated Saliva-Parotin-A preparation was largely retained. Remarkably large amount of radioactivity was demonstrated in the kidney after the intravenous injection of I¹³¹-labeled Saliva-Parotin-A to rats. Only a small localization of radioactivity was found in the liver and spleen which were the main and characteristic sites of localization of radioactivity after the administration of the labeled Parotin to rats.