抄録
Hypothalamic neurosecretory phenomena were histologically observed by means of Gomori's chrome-alum hematoxilin and phloxine method and compared with the function and enlargement of the residual thyroid in partially thyroidectomized rats.
The secretory activity of the supraoptic and paraventricular nuclei was temporarily elevated at the ends of 3 and 6 post operative days when the function and enlargement of thyroid were gradually increasing. On these days, the remarkable accumulations of CH positive materials in the nerve fibers leading from the cells of the both hypothalamic nuclei were observed on one hand, and on the other hand the increase of I131 uptake for 24 hrs., enlargement of thyroid and relative increase of T3 and T4 fractions in paper chromatogram were significantly raised in the residual thyroid of partially thyroidectomizcd rats.
The increase in size of cells in the hypothalamic nuclei was considered most significant in these experiments.
