Endocrinologia Japonica
Online ISSN : 2185-6370
Print ISSN : 0013-7219
ISSN-L : 0013-7219
STUDIES ON THE PHYSIOLOGICAL CHEMISTRY OF THE SALIVARY GLANDS XLIX. STABILITY OF PAROTIN IN AQUEOUS SOLUTION
YOSOJI ITOMASATO SHINODA
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1960 年 7 巻 4 号 p. 336-346

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Both the calcium activity and the leukocyte activity of parotin in aqueous solution (pH 8.0) were relatively stable against the incubation at 37°C. The calcium activity of parotin is labile in strong acid solution (pH 1.4), but is remarkably stable in strong alkaline solution (pH 12.6). In contrast to the calcium activity, the leukocyte activity of parotin is very stable in acid solution and extremely unstable in alkaline solution. The ultraviolet absorption maximum remained at 277mμ after incubation, and the extinction coefficient at that wave length showed slight increase in both solutions of pH 1.0 and pH 11.0 after incubation. No degradation or splitting of the molecule of parotin was demonstrated by paper partition chromatography, paper electrophoresis, or ultracentrifugation.
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© The Japan Endocrine Society
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