Endocrinologia Japonica
Online ISSN : 2185-6370
Print ISSN : 0013-7219
ISSN-L : 0013-7219
A PAROTIN-LIKE SUBSTANCE (α-PAROTIN) IN BOVINE PAROTID GLAND IV
STUDIES ON THE PHYSIOLOGICAL CHEMISTRY OF THE SALIVARY GLANDS LXI
HIDEICHI ASANO
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1961 Volume 8 Issue 3 Pages 205-209

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Abstract
α-Parotin was distinctly more effective on its hypocalcemic, leukokinetic, and calcification activities than parotin. The optimum dose of α-parotin on the calcification of rabbit incisor dentine was considered to be 50-100μg per kg.α-Parotin was unstable against heat and acid.α-Parotin also was inactivated by ketene, nitrous acid, formaldehyde, and iodine, but not by cysteine and thioglycollie acid. Amino and tyrosine-phenyl groups in α-parotin molecule were responsible for its biological activities.
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© The Japan Endocrine Society
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