Endocrine Journal
Online ISSN : 1348-4540
Print ISSN : 0918-8959
ISSN-L : 0918-8959
Development of Graves' Disease after Surgical Treatment for Thyroid Nodules
Report of Four Cases
YOSHIO KASUGASHINYA KOBAYASHIMINORU FUJIMORIKIYOSHI SHINGUYOSHIHISA HAMAKEN-ICHI ITOJUN AMANO
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JOURNAL FREE ACCESS

1997 Volume 44 Issue 4 Pages 567-570

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Abstract

We report herein rare cases who developed hyperthyroid Graves' disease after surgical treatments for thyroid nodules. We have seen only 4 such cases in the course of 1680 consective cases (0.24%) of thyroidectomies in which partial thyroidectomy was carried out from 1966 to 1993. It is of interest that because 2 of these three cases (67%) were associated with positive TGHA and/or MCHA at the time of surgery, the presence of autoimmune thyroiditis may predispose to Graves' disease, but surgical treatment of the thyroid glands may not be related to the development of Graves' disease, because the hyperthyroid symptoms appeared 2 to 27 years (mean: 12 years) after the surgery.

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© The Japan Endocrine Society
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