抄録
Understanding the extent of human exposure to chemicals such as pesticides, veterinary drugs, and feed additives in our daily diet is indispensable for ensuring food safety. The current methods used for exposure assessment lack detailed consideration of those chemicals consumed from mixed foods. To estimate the exposure from consumed foods, including mixed ones, a refined method was developed. This method incorporates food consumption data obtained from a nationwide dietary survey conducted in Japan, a reverse-yield factor that disaggregates mixed foods into raw primary commodity ingredients, and a processing factor that considers changes in the chemical residue concentration during processing. The short-term exposure was estimated based on the veterinary drug concentration detected in salmon, and the hazard quotient (HQ) was calculated by dividing the estimated exposure amount by the Acute Reference Dose. In the case of salmon consumption within the Japanese diet, the calculated HQs were found to be well below one, suggesting that there would be no unacceptable acute health risks associated with the detected residues in salmon.
