抄録
The activity of erythrocyte 5-aminolevulinic acid dehydratase (ALA-D) of carp Cyprinus carpio wasmeasured under a variety of lead exposure conditions. A two-week exposure of carp to water leadconcentrations of 10-1, 000 ppb strongly inhibited their ALA-D activities with increasing water leadconcentrations. When carp were exposed to water lead concentration of 100 ppb, depressed activity ofALA-D became visible after only 2 days, and this activity became even less with increasing exposureperiods. The ALA-D activity of carp after the fish were transferred from water lead concentration of 200 ppb to lead-free water recovered to only 50% of the value in the control fish even after four weeks. Therefore, these characteristics concerning ALA-D in carp blood indicate that this enzyme is useful asa short-term indicator of lead pollution in the fresh waters of Japan.
