Folia Pharmacologica Japonica
Online ISSN : 1347-8397
Print ISSN : 0015-5691
ISSN-L : 0015-5691
Pharmacological studies on extract of cattle prostate (PE) II. Effect of PE on respiration in prostate tissue of certain species.
Akihide KODAMasahiko HIRAMATSUYoichi YOSHIDA
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1974 Volume 70 Issue 1 Pages 65-70

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Abstract
A study was made of the effect of PE on respiration in prostate tissue of three species including rat, dog and human, in addition to that in the liver of the rat. In the prostate tissue of the rat, the respiration was distinctly higher than in the other species, and was increased by PE when citrate and/or succinate was used as a substrate. On the contrary, the degree of respiration in the liver of the rat was approx. one third compared to that in the prostate, and was slightly increased by PE, without a substrate or glucose. Respiration in the prostate tissue of the dog was dramatically increased when succinate was used as a substrate, but was hardly affected by glucose and citrate. PE increased the respiration in the presence of citrate and/or succinate as a substrate. Succinate increased dramatically, respiration in the prostate tissue from humans, the same of which was further re-inforced by PE with the same substrate.
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