Fundamental Toxicological Sciences
Online ISSN : 2189-115X
ISSN-L : 2189-115X
Toxicomics Report
Metabolomic analysis of low molecular weight substances released into medium from HEK293 cells treated with methylmercury
Takashi ToyamaGi-Wook HwangAkira Naganuma
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ジャーナル フリー

2015 年 2 巻 5 号 p. 227-228

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抄録
This study attempted to identify substances that are driven out of HEK293 cells by methylmercury. Metabolomic analysis revealed that the levels of 3-phenylpropionic acid, citrulline, lactic acid, ornithine, proline and beta-alanine in the cell culture medium were increased by the treatment of cells with methylmercury. Address to the mechanism underlying the release of these substances will provide useful information to elucidate the toxicity mechanism of methylmercury.
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© 2015 The Japanese Society of Toxicology
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