2022 Volume 64 Issue 7 Pages 1326-1331
A 66-year-old woman underwent upper gastrointestinal endoscopy, which revealed a whitish flat ridge (approximately 2 cm) with elongated villous protrusions covering the surface of the thoracic esophagus, together with small bumps, indicative of verrucous carcinoma (VC). Lugol chromoendoscopy showed lightly stained villous protrusions and dark staining of the base. Biopsy examination showed a slightly atypical cell type, and we could not exclude cancer, including VC; therefore, we performed ESD. Histopathological evaluation of the resected specimen confirmed diagnosis of a papilloma. Narrow-band imaging revealed villous protrusions with fine blood vessels without irregularity, similar to those observed in anemone-type papilloma. The aforementioned findings may be indicative of papilloma.