抄録
Seventy-two benign ulcerative lesions of the resected stomach were studied under the dissecting microscope. The appearance of the regenerative mucosa was com-pared in normally healing and slow healing ulcers. Usual healing course of a gastric ulcer : Four stages can be recognized in a gastric ulcer which heals com-pletely by the end of 3-months of medical treatment. Stage I : Initial stage. One layer of the regenerative epithelium at the margins. Stage II : Regenerative mucosa with a palisade-like appearance at the margins.Stage III : Red scar with a palisade-like appearance, Stage IV ; Red and white scar with a cobblestone appearance. Gastric ulcer showing protracted healing was deviled into three groups under the dissecting microscope. Group I : Small, shallow and irregular ulcer surro-unded by the regenerative mucosa with pale red, regular cobblestone appearance. Group II : Small, deep and irregular ulcer surroun-ded by the regenerative mucosa with red, irregular and uneven cobblestone appearance. Group III : Large and irregular ulcer surrounded by small multiple erosions and by the regenerative mucosa similar to group II The above classification can be applied to gastros-copic studies in clinical practice. Benign gastric ulcer without exacerbation follows either a normal healing course or a course of Group I. When an ulceration exacerbates during the protra-cted healing course of Group I, it takes the appeara-nce of Group III which in turn changes into that of Group II when a healing process occurrs. These three groups are closely related and interchangeable, and a slow healing ulcer is supposed to shift from one to another in a cycle.
