消化管粘膜の微細病変描出のためのmodel作製に関する研究

抄録

The purpose of this study is to make the same size model of the lesions of the digestive organs. Using silicon RTV gumm (KE-12) as the material, mould of the lesions of the freshly dissected organ were made, and using ultra-hard plaster or acryl-lesin-base the cast is made. The method was applied to the fresh, semi-fixed and fixed resected specimens and showed very clear replica of the original lesion especially the fine mucosal features. X-ray examination using Softex of the mould made it possible to study the fine mucosal changes of the lesion on the plain X-ray film. An attempt was made to apply the technique to the gastric ulcer through endoscopy. The mould of the gastric ulcer was made through gastroscope. The cast made from the mould helped in delineating the depth, size and mucosal changes of the ulcer lesion. The comparison of the histological findings with the findings obtainable by this new method will help in the understanding of the nature of the lesion as well as deminishing the exposure dose of the X-ray in the diagnosis of the gastric lesion. Preparation of the lesion for moulding, for instance how to make it dry enough, and the search for the more suitable moulding material remains to be investigated as well as the development of new fiberscope for this purpose.