早期胃癌の浸潤範囲の診断― Endoscopic Congo Red Testの効用とその後の改良―

抄録

1. The relation of fundal gastritis to the gross and histological type and location of early gastric cancer was examined by the endoscopic Congo red test. Results in-dicated a close correlation between the gross and histolo-gical type of cancer and the extent of fundal gastritis. In general, when there was little or no f undal gastritis, cancers were ulcerated and histologically undifferentiated, and they were chiefly located in nonacid-secreting areas adjacent to acid-secreting areas, or sometimes they were surrounded by acid-secreting areas. On the contrary, when fundal gastritis was extensive cancers were polypoid and histologically differentiated, they were located in nonacid-secreting areas far from acid-secreting areas. Therefore, it was possible to estimate exactly the extent of cancerous infiltration in 760 of the ulcerated and histologically undifferentiated cancers. However, it was difficult to determine the infiltration in differentiated ulcerated and polypoid cancers by this method. 2. The endoscopic Congo red test, combined with Methylene blue test, was developed in this clinic. This method makes it possible to determine the exact extent of the cancerous infiltration of the differentiated, ulcerated or polypoid, cancers.