REPAIR OF ULTRAVIOLET-INDUCED DAMAGE IN TRANSFORMING DNA OF BACILLUS SUBTILIS
1970 年 45 巻 1 号 p. 1-9
詳細
1970 年 45 巻 1 号 p. 1-9
UV damage induced in the DNA of uvr or uvs strains of Bacillus subtilis was repaired in uvr recipient cells, but no such repair occurred in uvs cells. Post-irradiation repair of UV damage induced in the DNA of the uvr strain was inferred from the increase in extractable transforming activity observed during post-irradiation incubation carried out before assaying with uvs recipient strains. No post-irradiation restoration of UV-irradiated transforming DNA was observed in uvs cells. Strain uvs-80 was able to excise thymine dimers from the DNA as did the uvr strain but lost extractable transforming activity rapidly during post-irradiation incubation.
