Genome Informatics
Online ISSN : 2185-842X
Print ISSN : 0919-9454
ISSN-L : 0919-9454
On Correlation between G+C Contents and Intron Lengths: Longer Introns Tend to be More A+T Rich
Yasuhiro AsakawaMasaru Tomita
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ジャーナル フリー

1996 年 7 巻 p. 184-185

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An interesting correlation between G+C contents and the lengths of primate introns have beenfound by our computer analysis.
All sequences of primate introns were extracted from the Genbank database and classifiedinto subgroups according to their lengths (the number of bases; increment of 100). G+C contents (%) were then calculated for each subgroup.
The results indicate that shorter introns tend to contain more G and C nucleotides, andlonger introns contain A and T nucleotides.
Frequencies of each nucleotide for each subgroup are shown in figure 1.
We also computed G+C contents of exons flanking those introns for each subgroup. As wecan see in figure 2, the similar but weaker tendencies are observed.
Biological significance of those observations is currently under investigation. We also intendto extend our analysis to other eukaryotes.
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© Japanese Society for Bioinformatics
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