尿酸
Online ISSN : 2187-0098
Print ISSN : 0388-4120
ISSN-L : 0388-4120
長期間観察しえたvon Gierke病の1例
特に血清尿酸値の推移に関して
織部 元廣平尾 修恭延永 正
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ジャーナル フリー

1982 年 6 巻 2 号 p. 148-153

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Eleven years follow up observation has been done in an adult patient with glycogen storage disease type 1 with special reference to the serum uric acid. In 1969 at the first visit to our hospital, he was 20 years old and his serum uric acid was 13.5 mg/dl. Serum uric acid was controlled under 8 mg/dl by administration of benzbromarone or allopurinol. As he felt well he stopped to take any drug since December 1971. Nevertheless his serum uric acid remained at 9.8mg/dl in January 1977 and it was rather lowered to 7.7 mg/dl in October 1980. Laboratory data in 1969 and 1980 showed that lipid metabolism was improved but glucose was not. Although the real reason is not clear, the partial deficiency of enzyme, or an adaptation of metabolism was considered for the spontaneous improvement of uric acid metabolism in this case.

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© 一般社団法人 日本痛風・核酸代謝学会
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