抄録
Cytidylate cyclase activity in rat brain was determined by EIA and the following results were obtained.
1) Cytidylate cyclase existed in a particulate fraction.
2) Cytidylate cyclase activity in brain was higher than other tissues.
3) The optimal pH of cytidylate cyclase was about 9.5.
4) Cytidylate cyclase activity was dependent on Mn++.
5) Km value of solubilized cytidylate cyclase was 0.0156mM.