To investigate the presence of hyperuricemia in 94 patients with solid malignant tumors, serum uric acid (SUA) were measured and the following results were obtained. 1. The mean SUA levels in patient s with liver cancer were highest. 2. Hyperuricemia with the SUA over 6.5 mg/dl and over 7.5 mg/dl were found in 19% and 7.5% of them respectively. Hypouricem ia with the SUA below 2.5 mg/dl was found in 7.4%. 3. There were no significant differences between the mean SUA levels in solid malignant patients with metastases and in those without metastases and also the mean SUA levels in patients with serum CEA over 5.0 ng/ml were not statistically significant compared to those with serum CEA below 5.0 ng/ml. 4. There were not characteristic clinical pictures in patients with hyperuricemia or hypouricemia.
