鼠癩の免疫に關する実驗的研究

第4篇 鼠癩菌死菌ワクチンによる白鼠の鼠癩感染防禦実驗

抄録

1) The vaccine of heat killed murine leprosy bacilli inhibits the onset of leproma in the inoculated site to some extent, but not the lesions in the viscera.
2) The liquid paraffine vaccine of murine bacilli not only prolongs the initiation of the leproma, but also prevents the growth of the organisms in the lymph nodes or in the viscera.
3) The liquid paraffine vaccine of the nonpathogenic acid-fasts No 16, prolongs the onset of leproma, but is not strong enough to give any influence on the occurrence of visceral changes.
4) The immunologic intensities of the three vaccines abovementioned can be arranged in the descending order as following; the liquid paraffine vaccine of the murine bacilli, the heat killed vaccine of the murine bacilli and the liquid paraffine vaccine of the nonpathogenic acid-fast.