抄録
This article presents a short review on high pressure (HP) effects ranging from the sub-megapascal to the hundreds of MPa range. The pressure needed to act on biosystems strongly correlates with their complexity and the level of differentiation. On the lower pressure scale, HP acts on whole organisms with HP levels <1 MPa for terrestrial mammals, up to 25 MPa for marine mammals and fish, and larger pressures for deep sea animals (<100 MPa). Large pressures (100 MPa to 1 GPa) are the domain of isolated HP effects on membranes, protein folding/unfolding and prokaryotes and thus important for sterilization and the food industry. Intermediate pressures of between 10 MPa and 100 MPa seem to be the domain for HP interactions with living cells of higher eukaryotes. As an example for HP Bioscience, some results from skeletal muscle are given.
