事象関連電位を用いた摂食前後の脳機能評価

抄録

The intense drowsiness that occurs after lunch is called the post-lunch dip (PLD), and it is known to reduce alertness and work efficiency. Although studies aimed at elucidating the mechanism of PLD generation have been actively conducted, the cause has not yet been elucidated. For this, it is essential to establish an objective evaluation index based on the brain activity index. In this paper, we focused on P300 and contingent negative variation (CNV), which are a kind of event-related potentials (ERP), as quantitative evaluation indices, and conducted a verification experiment to verify its effectiveness. The subjects were 14 healthy young people, and two pieces of bread and 285 ml of water were used for the dietary load. P300 and CNV were measured four times before ingestion, immediately after ingestion, and 40 and 80 min after ingestion; furthermore, the Stanford Sleepiness Scale (SSS) was performed before each measurement. As a result, a significant increase in SSS, and a significant decrease in the early and late CNV areas, a significant increase in P300 latency prolongation were confirmed 40 minutes after eating (p<0.05). This suggests that P300 and CNV may be useful as an objective evaluation index for PLD.