The objective of the present study was to evaluate the effect of extremely low frequency (ELF)-electric field (EF) treatment on decubitus ulcer. Hairless mice (Hr-/kud) were used, and ulcers were formed by magnetic compression of the back skin. The extent of the ulcer was assessed by the diameter of the wound and the crust area. The observation period was 14 days from the day of pressure. Three experimental groups were assigned: a group treated with EF from before the formation of the pressure ulcer until the end of observation, a group that started EF treatment on the day of magnet compression, and a control group that only had pressure ulcer formation. EF was generated at 50Hz at 10kV/m between parallel plate electrodes. EF treatment on the mice was 60 minutes per day. Results showed that the maximum wound diameter was reached in all groups for 3 days. Both decubitus ulcer diameter and crust diameter in the field-treated group were smaller than those in the control group, suggesting an inhibitory effect of ELF-EF on the process of decubitus ulcer development and repair.
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