Examination of Absorptiometry Microchip Application Aiming for Particle-Enhanced Turbidimetric Immunoassay

Abstract

In this paper, newly application of the absorptiometry microchip was considered and sensor property was characterized with real sample. C-reactive protein (CRP) measurement, that is one of the items of serology test, was chosen as first application. CRP value is very useful marker of irritation and also appropriate to confirm ability of sensor performance for Particle-Enhanced Turbidimetric Immunoassay (PETIA). Fabricated microchip shows characteristics equivalent to commercially available sensor unit. Sensor property with different concentration samples was also evaluated. Temperature effect for PETIA was described with characterized data. From the results of characterization and discussion, the microchip can be applicable for CRP measurement with PETIA.