Industrial Health
Online ISSN : 1880-8026
Print ISSN : 0019-8366
ISSN-L : 0019-8366
FUNCTIONAL CHANGES OF TESTES IN LEAD INTOXICATED RATS
A.ROY CHOWDHURYR. V. RAOA. K. GAUTAMS. K. KASHYAP
著者情報
ジャーナル フリー

1987 年 25 巻 2 号 p. 55-62

詳細
抄録
Lead acetate treatment intraperitoneally at the dosages of 1 mg, 2 mg, 4 mg and 6 mg/kg over a period of 30 days altered spermatogenesis in rats. Inhibition of Δ5-3β-hydroxysteroid dehydrogenase was parallel with the high concentration of testicular cholesterol and low concentration of ascorbic acid, alkaline phosphatase and protein in most of the treated groups. Gradual increase in blood and testis lead alongwith the proportional inhibition of δ-aminolevulinic acid dehydratase levels indicated the intensity of lead toxicity in rats. Data revealed that alteration of spermatogenesis in lead treated rats might be due to the inhibition of steroidogenesis.
著者関連情報
© National Institute of Occupational Safety and Health
前の記事 次の記事
feedback
Top