Lymphoplasmacytic Infiltration of Multiple Organs with Immunoreactivity for IgG4: IgG4related Systemic Disease

Takako Saeki; Akihiko Saito; Tohru Hiura; Hajime Yamazaki; Iwao Emura; Mitsuhiro Ueno; Syoji Miyamura; Fumitake Gejyo

doi:10.2169/internalmedicine.45.1431

CASE REPORTS

Lymphoplasmacytic Infiltration of Multiple Organs with Immunoreactivity for IgG4: IgG4related Systemic Disease

Takako Saeki, Akihiko Saito, Tohru Hiura, Hajime Yamazaki, Iwao Emura, Mitsuhiro Ueno, Syoji Miyamura, Fumitake Gejyo

著者情報

Takako Saeki
Department of Internal Medicine, Nagaoka Red Cross Hospital
Akihiko Saito
Department of Applied Molecular Medicine, Niigata University Graduate School of Medical and Dental Sciences
Tohru Hiura
Divisions of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences
Hajime Yamazaki
Department of Internal Medicine, Nagaoka Red Cross Hospital
Iwao Emura
Department of Pathology, Nagaoka Red Cross Hospital
Mitsuhiro Ueno
Divisions of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences
Syoji Miyamura
Department of Internal Medicine, Nagaoka Red Cross Hospital
Fumitake Gejyo
Divisions of Clinical Nephrology and Rheumatology, Niigata University Graduate School of Medical and Dental Sciences

キーワード: IgG4, autoimmune pancreatitis, Sjögren's syndrome, Mikulicz's disease, tubulointerstitial nephritis

ジャーナルオープンアクセス

2006 年 45 巻 3 号 p. 163-167

DOI https://doi.org/10.2169/internalmedicine.45.1431

詳細

抄録

We report three elderly men with high serum IgG4 concentrations and multiple lymphoplasmacytic inflammation of the salivary glands, lymph nodes, pancreas, and renal interstitium. The infiltrating plasma cells had strong immunoreactivity for IgG4, even in patients without pancreatic lesions. These cases show that IgG4 is associated not only with autoimmune pancreatitis, but also with other systemic lymphoplasmacytic disease.

責任著者(Corresponding author)

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