Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
Development of Hepatocellular Carcinoma (HCC)in a Patient 17 Years after Recovery from ChronicHepatitis B and Seroconversion to Anti-HBs
Shuichiro ShigematsuTeru KumagiYoichi HiasaTomorou YoshidaMasashi HirookaYoshio TokumotoBunzo MatsuuraKojiro MichitakaNorio HoriikeTaiji TohyamaMorikazu Onji
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ジャーナル オープンアクセス

2007 年 46 巻 1 号 p. 29-33

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A 63-year-old man was admitted to hospital in 2003 for treatment of a hepatocellular carcinoma (HCC). He was negative for HBs antigen (HBsAg) and anti-HCV antibody, and positive for anti-HBs. He had a past history of chronic hepatitis B. In 1986, HBsAg had become negative with the development of anti-HBs. In 2003, an HCC was detected and liver resection was carried out. Histological examination revealed moderately differentiated HCC and slightly fibrotic liver. It is suggested that a diagnosis of HCC, combined with negativity for HBsAg and anti-HCV antibody, may include cases of past recovery from chronic hepatitis B, such as this case.

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© 2007 by The Japanese Society of Internal Medicine
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